RADICAL TRACHELECTOMY: A 10-YEAR EXPERIENCE OF TOMSK CANCER RESEARCH INSTITUTE
##article.numberofdownloads## 77
##article.numberofviews## 275
PDF (Русский)

Keywords

CERVICAL CANCER
TRACHELECTOMY
IMPLANT
REPRODUCTIVE FUNCTION

How to Cite

Chernyshova, A., Kolomiets, L., Gyunter, V., & Marchenko, Y. (2019). RADICAL TRACHELECTOMY: A 10-YEAR EXPERIENCE OF TOMSK CANCER RESEARCH INSTITUTE. Voprosy Onkologii, 65(5), 715–720. https://doi.org/10.37469/0507-3758-2019-65-5-715-720

Abstract

The article summarizes and presents 10 years of experience in the organ-preserving treatment of invasive cervical cancer in patients of reproductive age in the amount of radical trachelectomy. The study included 68 patients with cervical cancer (T1a1NxM0 - T2aNxM0), the average age was 34.1 ± 8.4 years. Of these, 39 patients underwent radical trachelectomy with transabdominal access, 29 - with laparoscopic. During the operation, a mesh implant with a shape memory, woven into a stocking of super-elastic nickel-titanium filament with subsequent fixation with separate sutures along the perimeter, was used to form the locking apparatus of the uterus and strengthen the utero-vaginal anastomosis. It has been shown to be highly effective for providing a “locking” effect of the cervix. Of all the patients treated, 15 (22%) spontaneous pregnancies were registered, 9 after PAT and 6 after RT with laparoscopic access, of which 3 had operative delivery in terms of 29, 31 and 38 weeks. One currently has a prolongation of pregnancy (33 weeks), 2 (13.3%) had spontaneous miscarriages, the rest interrupted the pregnancy for various reasons. The onset of pregnancy was noted in patients after laparoscopic RT within a shorter period after surgery from 3 to 18 months. Menstrual dysfunction after surgery was observed in 4% and 19%, respectively. Dysfunctional uterine bleeding prevailed. The median follow-up was 69 months; 1 relapse was detected (1.4%). Overall survival rate of 100%.

https://doi.org/10.37469/0507-3758-2019-65-5-715-720
##article.numberofdownloads## 77
##article.numberofviews## 275
PDF (Русский)

References

Hurria A., Levit L.V., Dale W. et al. Improving the Evidence Base for Treating older Adults With Cancer: American society of Clinical oncology statement // J. Clin. Oncol. -2015. - Vol. 33(32). - P 3826-3833. - PMID: 26195697. DOI: 10.1200/JCO.2015.63.0319.PMID

Concise Report on the World Population Situation in 2014. New York: United Nations, 2014. - 30 p.

Colombo N., Preti E., Landoni F. et al. ESMO Guidelines Working Group. Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up // Ann Oncol. - 2013. - Suppl 6. - vi33-8. - DOI: 10.1093/annonc/mdt353

Чернышова А.Л., Коломиец Л.А., Красильников С.Э. Органосохраняющее лечение при инвазивном раке шейки матки // Сибирский онкологический журнал. - 2011. - № 2. - С. 72-78.

Антипов В.А., Новикова Е.Г., Балахонцева О.С., Шевчук А.С. Особенности функциональной и анатомической реабилитации после радикальной абдоминальной трахелэктомии // Проблемы репродукции. - 2010. - № 1. - С. 103-107.

Чернышова А.Л, Коломиец Л.А., Синилкин И.Г. и др. Оптимизация подходов к выбору объема хирургического лечения у больных раком шейки матки (роль исследования сторожевых лимфоузлов) // Вопросы онкологии. - 2016. - Т. 62. - № 6. - С. 807-1 1 1.

Антипов В.А., Новикова Е.Г., Балахонцева О.С., Шевчук А.С. Радикальная абдоминальная трахелэктомия: технические аспекты // Вопросы онкологии. - 2010. - Т. 56. - № 1. - С. 36-42.

Чернышова А.Л., Ляпунов А.Ю., Коломиец Л.А. и др. Определение сторожевых лимфатических узлов при хирургическом лечении рака шейки матки // Сибирский онкологический журнал. - 2012. - № 3. - С. 28-33.

Wuntakal R., Papadopoulos A.J., Montalto S.A. et al. Location of Sentinel Lymph Node in Cervical Carcinoma and Factors Associated With Unilateral Detection // Gynecol Cancer. - 2015. - Vol. 25(9). - P. 1663-1668.

Tax C., Rovers M.M., de Graaf C. et al. The sentinel node procedure in early stage cervical cancer, taking the next step; a diagnostic review // Gynecol. Oncol. - 2015. - Vol. 139(3). - P. 559-567.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

© АННМО «Вопросы онкологии», Copyright (c) 2019