Vol. 66 No. 3 (2020), CLINICAL CASE

Vol. 66 No. 3 (2020)

CASE OF CYTOMORPHOLOGICAL DIAGNOSIS OF PANCREATIC SCHWANNOMA

CLINICAL CASE

https://doi.org/10.37469/0507-3758-2020-66-3-296-301

Published 01.03.2020

A. Mikhetko⁺⁻
Anna Artemeva⁺⁻
Olga Ivko⁺⁻
Oleg Tkachenko⁺⁻
Marina Grinkevich⁺⁻
Aleksandra Sidorova⁺⁻
Yuriy Petrik⁺⁻
A. Vasiliev⁺⁻
Inna Amelina⁺⁻
Aleksey Karachun⁺⁻
Yuriy Pelipas⁺⁻
Konstantin Lebedev⁺⁻

A. Mikhetko

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Anna Artemeva

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Olga Ivko

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Oleg Tkachenko

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Marina Grinkevich

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Aleksandra Sidorova

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Yuriy Petrik

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

A. Vasiliev

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Inna Amelina

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Aleksey Karachun

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Yuriy Pelipas

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

Konstantin Lebedev

N. N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

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Keywords

PANCREAS
SCHWANNOMA
CYTOMORPHOLOGICAL DIAGNOSIS
IMMUNOCYTOCHEMICAL STUDY
SURGICAL TREATMENT

How to Cite

Mikhetko, A., Artemeva, A., Ivko, O., Tkachenko, O., Grinkevich, M., Sidorova, A., Petrik, Y., Vasiliev, A., Amelina, I., Karachun, A., Pelipas, Y., & Lebedev, K. (2020). CASE OF CYTOMORPHOLOGICAL DIAGNOSIS OF PANCREATIC SCHWANNOMA. Voprosy Onkologii, 66(3), 296–301. https://doi.org/10.37469/0507-3758-2020-66-3-296-301

Abstract

Background: Schwannoma is an extremely rare non-epithelial tumor of the pancreas. Less than 50 cases of pancreatic schwannoma have been described in the literature over the past thirty years and only few cases report has described its findings on Fine-Needle Aspiration (FNA). Preoperative diagnosis of pancreatic schwannoma can be particularly challenging. Pancreatic schwannomas may mimic other, more common pancreatic lesions, such as cystic neoplasms, solid neoplasms, neuroendocrine tumors. Cytomorphological verification of the diagnosis is difficult due to the similarity of Schwannomas with other non-epithelial tumors from spindle cells. Therefore, pancreatic schwannomas have a very high rate of misdiagnosis. Objective: demonstration preoperative diagnosis and treatment of a rare pancreatic tumor. Materials and methods: Here we present a case of preoperative cytomorphological diagnosis of pancreatic schwannoma in a 58-year-old man. During magnetic resonance imaging, computed tomography and endosonography (EUS), the patient was diagnosed the tumor in the head of the pancreas with a diameter of up to 7 cm. For morphological verification of the process, a fine needle aspiration puncture of the formation was performed under EUS control. Diagnosis of pancreatic schwannoma was established by cytomorphological examination of cell block material using immunocytochemical method. Conclusion: the analysis of the result of cytomorphological diagnosis of pancreatic schwannoma is presented.

https://doi.org/10.37469/0507-3758-2020-66-3-296-301

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##article.numberofviews## 236

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References

Ercan M., Aziret M., Bal A. et al. Pancreatic schwannoma: A rare case and a brief literature review. // International Journal of Surgery Case Reports. - 2016. - Vol. 22 - P. 101 -104.

Bruno M., Maletta F., Gaia S. et al. Wait-and-See Policy for a Small Pancreatic Schwannoma Diagnosed With Endoscopic Ultrasound With Fine-Needle Aspiration // ACG Case Rep J. - 2019. - Vol. 6. - № 3. - P. 1-3.

Zhang X., Siegelman E. S., Lee M. K., Tondon R. Pancreatic schwannoma, an extremely rare and challenging entity: Report of two cases and review of literature // Pancreatology. - 2019. - Vol. 19. - № 5. - P 729 -737.

Doxtader E.E., Sturgis C.D., Dyhdalo K.S. Cystic pancreatic schwannoma diagnosed by endoscopic ultrasound-guided fine needle aspiration // Diagnostic Cytopathology. - 2018. - Vol. 46. - № 10. - P 1-3.

Tafe L.J., Suriawinata A.A. Cystic pancreatic schwannoma in a 46-year-old man // Annals of Diagnostic Pathology. - 2008. - Vol. 12. - № 4. - P. 296-300.

Wang H., Zhang B., Wang S. et al. Pancreatic schwannoma: Imaging features and pathological findings // Hepatobiliary & Pancreatic Diseases International. - 2019. - Vol. 18. - № 5. - P. 493-494.

Hayashi K., Tsuchiya A., Ikarashi S. et al. A Case of Pancreatic Schwannoma Diagnosed Preoperatively by Endoscopic Ultrasonography-Guided Fine Needle Aspiration and Treated with Laparoscopic Surgery // Journal of Pancreatic Cancer. - 2018. - Vol. 4. - №1. - P 7-10.

Takasumi M., Hikichi T., Takagi T. et al. Efficacy of endoscopic ultrasound-guided fine-needle aspiration for schwannoma: six cases of a retrospective study // Fukushima J. Med. Sci. - 2017. - Vol. 63. - № 2. - P 75-80.

Ciledag N., Arda K., Aksoy M. Pancreatic schwannoma: A case report and review of the literature // Oncology Letters. - 2014. - Vol. 8. - № 6. - P. 2741-2743.

Ma Y, Shen B., Jia Y et al. Pancreatic schwannoma: a case report and an updated 40-year review of the literature yielding 68 cases // BMC Cancer. - 2017. - Vol. 17. - P. 853.

Буткевич А.Ц., Сорокин М.Н., Богданов С.Н. и др. Шваннома крючковидного отростка поджелудочной железы // Анналы хирургической гепатологии. - 2015. - Т. 20. - № 4. - С. 105-109.

Mizuno N., Hara K., Hijioka S. et al. Current Concept of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Pancreatic Cancer // Pancreatology. - 2011. - Vol. 11. - № 2. - P. 40-46.

Pitman M.B., Layfield L.J. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology. Definitions, Criteria, and Explanatory Notes // Springer Cham Heidelberg New York Dordrecht London, 2015. - 96 с.

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