COLORECTAL CANCER AND FEATURES OF ITS METASTASIS
PDF (Русский)

Keywords

RECTAL CANCER
COLON CANCER
COLORECTAL CANCER
COMBINED TREATMENT
DISTANT METASTASES

How to Cite

Vlasov, O., Tkachev, S., & Prorokov, V. (2017). COLORECTAL CANCER AND FEATURES OF ITS METASTASIS. Voprosy Onkologii, 63(3), 450–455. https://doi.org/10.37469/0507-3758-2017-63-3-450-455

Abstract

The article analyzes the frequency of regional metastasis detection in patients with operative colorectal cancer as well as the frequency and patterns of the appearance of distant metastases depending on the presence or absence of regional metastases, tumor localization and the method of treatment. It was found that the frequency of distant metastases in colorectal cancer depended mainly on the presence or absence of metastases in the regional lymph nodes. Some influence on the decrease in the frequency of distant metastasis was exacerbated by the preoperative radiation exposure by radiomodifiers and on the increase - the interval between the end of the radiation treatment phase and the moment of surgery. In rectal cancer the localization of distant metastases depended on the level of tumor localization. In colon cancer the major part (81.6%) of distant metastases was located in the liver, the rest 18.4% -extrahepatic and was represented by peritoneum dissemination, metastases in the ovary and retroperitoneal lymph nodes. Among colon cancer patients after the combined treatment there were no cases of tumor dissemination through the abdominal cavity and the appearance of lymphogenous metastases.
https://doi.org/10.37469/0507-3758-2017-63-3-450-455
PDF (Русский)

References

Барсуков Ю.А. Комплексное лечение больных раком прямой кишки с использованием полирадиомодификации и системного цитотоксического компонента в схемах неоадъювантной лучевой терапии // Онкол. колопроктол. - 2011. - № 1. - С. 5 - 10.

Бердов Б.А. Лучевая терапия в комбинированном лечении рака прямой кишки // Хирургия. - 1989. - № 5. - С. 39 - 43.

Власов О.А., Барсуков Ю.А., Ткачев С.И. и др. Комбинированное лечение больных раком прямой кишки с регионарными метастазами (T2-3N1-2M0) // Онкол. колопроктол. - 2011. - № 3. - С. 41 - 45.

Кныш В.И. Рак прямой и ободочной кишки. - М., 2003. - 250 с.

Неттер Ф. Атлас анатомии человека: Уч. пос.-атлас / Под. ред. Н.О. Бартоша; Пер. с англ. А.П. Киясова. -М.: ГЭОТАР-МЕД, 2003. - 600 с.

Пророков В.В., Голдобенко Г.В., Николаев А.В. и др. Отдаленные результаты хирургического лечения больных раком ободочной кишки с предоперационной ги-поксирадиотерапией // Вопр. онкол. - 2011. - Т. 57. - № 1. - С. 99 - 101.

Babini L., Minaci G., Emiliani E. The role of radiotherapy in the management of rectum and rectosigmoid adenocarcinoma // Libri oncol. - 1984. - Vol. 13. - P. 125-128.

Dwight R., Higgins G., Roswit B. et al. Preoperative radiation and surgery for cancer of the sigmoid colon and rectum // Amer. J. Surg. - 1972. - Vol. 123. - P 93-103.

Hoskins R.B., Gunderson L.L., Desorets D.E. et al. Adjuvant postoperative radiotherapy in carcinoma of the rectum and rerctosigmoid // Cancer (Philad.). - 1985. -Vol. 55. - P. 61-71.

De Caluwe L., Van Nieuvenhove Y, Ceelen W.P Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer // Cochrane Database Syst. Rev. - 2013. - Vol. 2. - CD006041.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

© АННМО «Вопросы онкологии», Copyright (c) 2017