MODELING OF SOLID LIVER CANCER IN A RABBIT

ORIGINAL ARTICLES. B. EXPERIMENTAL RESEARCH

https://doi.org/10.37469/0507-3758-2017-63-5-785-791

Published 01.05.2017

Andrey Panchenko⁺⁻
Yevgeniy Plakhov⁺⁻
Yekaterina Gubareva⁺⁻
Lyudmila Guzevatykh⁺⁻
K. Khitrin⁺⁻
V. Balabanyan⁺⁻

Andrey Panchenko

N.N. Petrov National Medical Research Center of Oncology

Yevgeniy Plakhov

N.N. Petrov National Medical Research Center of Oncology

Yekaterina Gubareva

N.N. Petrov National Medical Research Center of Oncology

Lyudmila Guzevatykh

Ltd “Technology of Medicines"

K. Khitrin

Ltd “Technology of Medicines"

V. Balabanyan

Ltd “Technology of Medicines"

PDF (Русский)

Keywords

ОПУХОЛЬ VX2
MODEL OF LIVER CANCER
LEUKOCYTOSIS
RABBIT
COMPUTED TOMOGRAPHY
MICROSPHERES
VX2 TUMOR
TUMOR TRANSPLANTATION

How to Cite

Panchenko, A., Plakhov, Y., Gubareva, Y., Guzevatykh, L., Khitrin, K., & Balabanyan, V. (2017). MODELING OF SOLID LIVER CANCER IN A RABBIT. Voprosy Onkologii, 63(5), 785–791. https://doi.org/10.37469/0507-3758-2017-63-5-785-791

Abstract

Possibilities of the liver tumor modeling were assessed in rabbits of Soviet Chinchilla strain by implantation into the left lobe of the liver slices of squamous cell VX2 tumor obtained from donor rabbits inoculated with the tumor in the thigh muscles. The basic parameters of the model were established - the dynamics of tumor growth, inoculation rate, incidence of concomitant abdominal tumors. There was offered a method for minimally invasive monitoring of the development of the tumor after implantation to the liver by means of the level of venous blood granulocytes. It was found that the most appropriate way to diagnose liver tumors in rabbits was computed tomography scan.

https://doi.org/10.37469/0507-3758-2017-63-5-785-791

PDF (Русский)

References

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