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Abstract
This review discusses surgical management options, both radical and palliative surgical management for malignant pleural disease in lung cancer. No current clinical guideline recommends their routine implementation. Nevertheless, radical surgical management is used to improve the long-term results for patients with malignant pleural disease. The observational data suggest the effectiveness is not apparent, which is also associated with the patients’ heterogeneity and surgical methods. Most experts agree that it is impossible to draw well-grounded conclusions about the feasibility, efficacy, safety and optimal scope for surgical interventions in lung cancer patients with malignant pleural diseases. They advocate further research and randomised trials, considering the expected potential of using modern multidisciplinary approaches. When determining the tactics of malignant pleural disease management, an individual approach is required. It is crucial to consider the most significant prognostic and predictive factors: laterality, tumour spread (distant and regional metastases), sex, age, comorbidities, morphology, the presence of driver mutations, and the risk of postoperative complications. Personalisation of methods for managing malignant pleural disease in lung cancer is a promising area of modern oncology. However, many aspects of approaches to solving this problem remain unclear and require further research.
References
Арсеньев А.И., Нефедов А.О., Левченко Е.В. и соавт. Оптимизация методов лечения хирургических осложнений при раке лёгкого // Вопросы онкологии. 2012;58(5):674–679.
Arrieta O, Escamilla-López I, Lyra-González I et al. Radical aggressive treatment among non-small cell lung cancer patients with malignant pleural effusion without extra-thoracic disease // J. Thorac. Dis. 2019;11(2):595–601.
Bibby AC, Dorn P, Psallidas I et al. ERS/EACTS statement on the management of malignant pleural effusions // Eur. Respir. J. 2018;52:1800349. doi:10.1183/13993003.00349-2018
Chiang CL, Wang LC, Ho HL et al. Effect of postoperative systemic therapy on pulmonary adenocarcinoma with unexpected pleural spread detected during thoracotomy or thoracoscopy // Oncotarget. 2017;9(4):5435–5444.
Chikaishi Y, Shinohara S, Kuwata T et al. Complete resection of the primary lesion improves survival of certain patients with stage IV non-small cell lung cancer // J. Thorac. Dis. 2017;9(12):5278–5287.
Dai C, Ren Y, Xie D et al. Does lymph node metastasis have a negative prognostic impact in patients with NSCLC and M1a disease? // J. Thorac. Oncol. 2016;11(10):1745–1754.
Dall K, Ford C, Fisher R, Dunningc J. Is there a survival advantage of incomplete resection of non-small-cell lung cancer that is found to be unresectable at thoracotomy? // Interact. Cardiovasc. Thorac. Surg. 2013;16(4):529–532.
David EA, Clark JM, Cooke DT et al. The Role of Thoracic Surgery in the Therapeutic Management of Metastatic Non-Small Cell Lung Cancer // J. Thorac. Oncol. 2017;12(11):1636–1645.
Feller-Kopman DJ, Reddy CB et al. On behalf of the American Thoracic Society, Society of Thoracic Surgeons, and Society of Thoracic Radiology. Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline // Am. J. Respir. Crit. Care Med. 2018;198(7):839–849.
Fukui T, Yokoi K. The role of surgical intervention in lung cancer with carcinomatous pleuritic // J. Thorac. Dis. 2016;8(11):901–907.
Fukuse T, Hirata T, Tanaka F, Wada H. The prognostic significance of malignant pleural effusion at the time of thoracotomy in patients with non-small cell lung cancer // Lung Cancer. 2001;34(1):75–81.
Go T, Misaki N, Matsuura N et al. Role of surgery in multi-modality treatment for carcinomatous pleuritic in patients with non-small cell lung cancer // Surg. Today. 2015;45(2):197–202.
Guinde J, Georges S, Bourinet V et al. Recent developments in pleurodesis for malignant pleural disease // Clin. Respir. J. 2018;12:2463–2468.
Ichinose Y, Tsuchiya R, Koike T et al. The prognosis of patients with non-small cell lung cancer found to have carcinomatous pleuritic at thoracotomy // Surg. Today. 2000;30(12):1062–1066.
Ichinose Y, Tsuchiya R, Koike T et al. Prognosis of resected non-small cell lung cancer patients with carcinomatous pleuritis of minimal disease // Lung Cancer. 2001;32(1):55–60.
Iida T, Shiba M, Yoshino I et al. Surgical intervention for non-small-cell lung cancer patients with pleural carcinomatosis: results from the Japanese Lung Cancer Registry in 2004 // J. Thorac. Oncol. 2015;10(7):1076–1082.
Jin WB, Liang CY, Peng YH, Zhou N.K. Pleuropneumonectomy for diffuse pleural metastasis in primary lung cancer // J. Cancer. Res. Ther. 2013;9:92–97.
Koegelenberg CFN, Shaw JA, Irusen E.M, Gary Lee YC. Contemporary best practice in the management of malignant pleural effusion // Ther. Adv. Respir. Dis. 2018;12:1–13.
Kodama K, Higashiyama M, Okami J et al. Cytoreductive surgery and post-operative heated pleural chemotherapy for the management of pleural surface malignancy // Int. J. Hyperthermia. 2013;29(7):653–662.
Li C, Kuo SW, Hsu HH et al. Lung adenocarcinoma with intraoperatively diagnosed pleural seeding: is main tumor resection beneficial for prognosis? // J. Thorac. Cardiovasc. Surg. 2018;155(3):1238–1249.
Li H, Sun Z, Yang F et al. Primary tumour resection in non-small-cell lung cancer patients with ipsilateral pleural dissemination (M1a): a population-based study // Eur. J. Cardiothorac. Surg. 2019;55(6):1121–1129.
Li S, Zhang S, Huang M et al. Management of occult malignant pleural disease firstly detected at thoracotomy for non-small cell lung cancer patients // J. Thorac. Dis. 2019;9(10):1121–1129.
Liu T, Liu H, Wang G. Survival of M1a non-small cell lung cancer treated surgically: a retrospective single-center study // Thorac. Cardiovasc. Surg. 2015;63(7):577–582.
Migliore M, Calvo D, Criscione A et al. Cytoreductive surgery and hyperthermic intrapleural chemotherapy for malignant pleural diseases: preliminary experience // Future Oncol. 2015;11:47–52.
Mordant P, Arame A, Foucault C et al. Surgery for metastatic pleural extension of non-small-cell lung cancer // Eur. J. Cardiothorac. Surg. 2011;11:47–52.
Morgensztern D, Waqar S, Subramanian J et al. Prognostic impact of malignant pleural effusion at presentation in patients with metastatic non-small-cell lung cancer // J. Thorac. Oncol. 2019;7(10):1485–1489.
Okamoto T, Iwata T, Mizobuchi T et al. Pulmonary resection for lung cancer with malignant pleural disease first detected at thoracotomy // Eur. J. Cardiothorac. Surg. 2012;41(1):25–30.
Ost DE, Niu J, Zhao H et al. Quality Gaps and Comparative Effectiveness of Management Strategies for Recurrent Malignant Pleural Effusions // Chest. 2018;153(2):438–452.
Porcel JM, Lui MMS, Lerner AD et al. Comparing approaches to the management of malignant pleural effusions // Expert Review of Respiratory Medicine. 2017. doi:10.1080/17476348.2017.1300532
Ren Y, Dai C, Shen J et al. The prognosis after contraindicated surgery of NSCLC patients with malignant pleural effusion (M1a) may be better than expected // Oncotarget. 2016;7(18):26856–26865.
Ren YJ, She YL, Dai CY et al. Primary tumour resection showed survival benefits for non-small-cell lung cancers with unexpected malignant pleural dissemination // Interact. CardioVasc. Thorac. Surg. 2016;22(3):321–326.
Ryu JS, Ryu HJ, Lee SN et al. Prognostic impact of minimal pleural effusion in non-small-cell lung cancer // Clin Oncol. 2014;32(9):960–967.
Sawabata N, Matsumura A, Motohiro A et al. Malignant minor pleural effusion detected on thoracotomy for patients with non-small cell lung cancer: is tumor resection beneficial for prognosis? // Ann. Thorac. Surg. 2002;73(2):412–415.
Shen H, Cao Y, Li X. et al. Surgical Intervention Improves Survival for Metastatic Non-Small Cell Lung Cancer Patients // Medicine (Baltimore). 2016;95(21):3800.
Shiba M, Kakizawa K, Kohno H et al. Prognostic implication of Ki-67 immunostaining in treating subclinical pleural cancer found at thoracotomy in lung cancer patients // Ann. Thorac. Surg. 2001;71(6):1765–1771.
Xu Y, Chen N, Wang Z et al. Should primary tumor be respected for non-small cell lung cancer with malignant pleural disease unexpectedly found during operation? —a systemic review and metaanalysis // J. Thorac. Dis. 2016;8(10):2843–2852.
Yamaguchi M, Ichinose Y, Shimamatsu S et al. Preoperative concurrent chemoradiotherapy followed by extrapleural pneumonectomy for patients with non-small cell lung cancer with malignant pleural effusion and/or pleural nodules: ten-year results of a prematurely terminated single institute phase II trial // Surg. Oncol. 2015;24(2):78–83.
Yokoi K, Matsuguma H. Surgical treatment of lung cancer with carcinomatous pleuritic // Nihon Geka Gakkai Zasshi. 2013;114(4):196–200.
Yun JK, Kim MA, Choi CM et al. Surgical outcomes after pulmonary resection for non–small cell lung cancer with localized pleural seeding first detected during surgery // Thorac. Cardiovasc. Surg. 2018;66(2):142–149.
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