Voprosy onkologii

Current Issue

Vol. 71 No. 5 (2025)

Published 05.11.2025

The scientific and practical journal "VOPROSY ONKOLOGII" is the official peer-reviewed publication of the Federal State Budgetary Institute N.N. Petrov National Medical Research Center of Oncology Ministry of Health of the Russian Federation. It has been published since 1928. The journal is dedicated to the study of malignant neoplasms and their treatment. It is included in the list of leading peer-reviewed scientific publications of the Higher Attestation Commission of Russia (НАС), recommended for the publication of articles containing materials of candidate and doctoral dissertations. The publication is indexed by the Scopus, Russian Science Citation Index (RSCI) based on Web of Science.

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Журнал № 5-2025 (Русский)

FROM EDITION

985-985

Introductory Remarks, Doctor of Medical Sciences, Professor Novikov S.N.

https://doi.org/10.37469/0507-3758-2025-71-5-985-985

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ORIGINAL ARTICLES. CLINICAL RESEARCH

Ruslan I. Zagirov , Yury Yurevich Trunin, Nataliya Konstantinovna Serova , Nataliya Aleksandrovna Sergeeva , Mikhail Viktorovich Galkin , Igor Nikolaevich Pronin , Anastasia Sergeevna Kuznetsova , Andrey Vladimirovich Golanov

OF-2318

Hypofractionated Stereotactic Radiotherapy for Optic Nerve Sheath Meningiomas

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2318

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Andrey Sergeevich Chuguev, Vyacheslav Alekseevich Gerasimov, Andrey Dmitrievich Kaprin, Pavel Vladimirovich Datsenko

OF-2206

Results of the Study of Two Fractionation Regimens in Grade 4 Gliomas

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2206

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##article.numberofdownloads## 18

##article.numberofviews## 73

Kira E. Medvedeva , Igor A. Gulidov , Alyona A. Lemaeva, Sergei A. Ivanov, Andrey D. Kaprin

OF-2427

Safety and Efficacy of Re-irradiation with Pencil Beam Scanning Proton Therapy for High-Grade Glioma

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2427

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##article.numberofviews## 51

Ksenia Alexandrovna Chizhova, Dmitry A. Gulyaev , Vladislav Yurievich Chirkin, Ivan Alexandrovich Kurnosov

OF-2276

Influence of Extent of IDH Wild-Type Glioblastoma Resection on Survival

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2276

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Alyona Alekseevna Lemaeva, Igor Aleksandrovich Gulidov, Kira Evgenevna Medvedeva, Sergey Anatolevich Ivanov, Andrey Dmitrievich Kaprin

OF-2426

Efficacy and Safety of Proton Therapy for Skull Base Chordomas and Chondrosarcomas: An Analysis of Three-Year Outcomes

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2426

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##article.numberofdownloads## 11

##article.numberofviews## 50

Aleksej Vladimirovich Kozlov, Pavel Gadel'garaevich Tarazov , Julija Nikolaevna Vinogradova , Denis Sergeevich Kolesnikov , Andrej Evgen'evich Demko , Luiza Ibragimovna Korytova , Andrej Anatol'evich Stacenko , Anastasija Sergeevna Butrimova , Dmitrij Anatol'evich Granov

OF-2401

Resectable Pancreatic Head Cancer in High Surgical Risk Patients: Regional Chemotherapy Combined with Radiation versus Surgical Resection

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2401

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##article.numberofviews## 82

Damir Ichshanov, Marina V. Chernykh , Valerii Ivanov Ivanov , Evgeny Petukhov, Evgeny Rybakov, Alexey Moskalenko

OF-2380

Comparison of Immediate Outcomes of Neoadjuvant Radiotherapy for Rectal Cancer During the COVID-19 Pandemic. A Propensity Score-Matched Multicenter Retrospective Study

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2380

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##article.numberofdownloads## 11

##article.numberofviews## 47

Sergey N. Novikov, Elena I. Tiuriaeva, Roman V. Novikov, Denis V. Samsonov, Pavel Y. Grishko, Marina V. Grinkevitch, Alexey M. Karatchun, Oleg B. Tkatchenko, Elena V. Tkatchenko, Yulia S. Melnik, Yulia P. Shishkanova, Olga I. Ponomareva, Sergey S. Litinsky, Сергей Валерьевич Кондратьев, Maxim I. Sluzhev, Alexandr V. Kornilov, Alexandra Y. Olkina, Alexandra N. Sidorova, Liia M. Savel'eva, Anton Y. Zozulia, Sergey V. Kanaev, Alexey M. Belyaev

OF-2482

High-Dose-Rate Endorectal Brachytherapy Boost for Low-Lying Rectal Cancer: Predictors of Complete Clinical Response

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2482

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##article.numberofviews## 74

Yuri Andreevich Barsukov, Zaman Zaur ogly Mamedli, Vyacheslav Afendievich Aliev, Oleg Aleksandrovich Vlasov, Zaurbek Alihanovich Dudaev

OF-2245

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2245

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##article.numberofdownloads## 15

##article.numberofviews## 71

Ekaterina Samartseva, Sergey Novikov, Nikolay Ilyin, Yuri Merezhko, Roman Novikov, Maria Gotovchikova, Julia Melnik, Olga Ponomareva, Philip Antipov, Nikita Kuznetsov, Sergey Kanaev

OF-2451

Moderate hypofractionation of dose in pelvic lymph node irradiation for patients with high and very high risk prostate cancer: preliminary results

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2451

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##article.numberofdownloads## 24

##article.numberofviews## 87

Nikita O. Kuznetsov , Roman Vladimirovich Novikov, Sergey Nikolaevich Novikov, Екатерина Евгеньевна Самарцева, Nikolay Dmitrievich Ilin, Ivan Georgievich Gafton, Yuriy Olegovich Merezhko, Philip Evgenievich Antipov, Maria Yurivna Gotovchikova, Yulia Sergeevna Melnik, Olga Igorevna Ponomareva, Sergey Vasilievich Kanaev

OF-2375

Efficacy and Safety of Postoperative Stereotactic Radiotherapy to the Prostate Bed (Long-Term Follow-Up Results)

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2375

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##article.numberofdownloads## 6

##article.numberofviews## 83

Vasili Kirillovich Karandashov, Roman Vladimirovich Novikov, Ekaterina Sergeevna Kruglova, Olga Igorevna Ponomareva, Ilia Alexandrovich Burovik, Stanislav Alexandrovich Tyatkov, Anna Vasilievna Kulish, Georgii Alexandrovich Liasovich, Vladimir Vladimirovich Protoshchak, Sergey Nikolaevich Novikov

OF-2234

Role of Perineal Implantation of a Paraprostatic Spacer in Maintaining Erectile Function after Radiation Therapy

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2234

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##article.numberofviews## 91

Inna Vladimirovna Sycheva, Natalia Viktorovna Severskaya, Sergey Anatolyevich Ivanov, Andrey Dmitrievich Kaprin

OF-2462

Combined Treatment of Late Grade III Radiation Proctitis with the Use of Formalin of Reduced Concentration

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2462

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##article.numberofdownloads## 8

##article.numberofviews## 64

Anna A. Medvedeva, Vladimir I. Chernov, Maria S. Larkina Larkina, Olga S. Zebzeeva, Roman V. Zelchan, Anastasia N. Rуbina, Ruslan N. Varvashenya, Ekaterina А. Bezverkhniaia, Vladimir М. Tolmachev, Anna М. Orlova Orlova

OF-2438

A New PSMA-targeted Radiopharmaceutical for Single-Photon Emission Computed Tomography

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2438

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##article.numberofdownloads## 5

##article.numberofviews## 95

Anna A. Ivanova, Darya V. Ryzhkova, Andrei A. Stanzhevskii, Kseniia E. Sanarova, Darya A. Vazhenina, Aleksey D. Maistrenko, Maksim V. Artemov, Dmitry N. Maystrenko

OF-2267

Comparative Performance of 68Ga-FAPI-04 and ¹8F-FDG PET/CT for Detection of Malignant Tumors and Metastases

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2267

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##article.numberofdownloads## 20

##article.numberofviews## 96

Andrey A. Stanzhevskiy, Oleg E. Molchanov, Dmitriy N. Maistrenko, Daria A. Vazhenina , Maria V. Odintsovа, Anna A. Ivanova, Larisa A. Chipiga, Valeria B. Nomokonova

OF-2250

Initial Clinical Experience with Established and Novel Radiopharmaceuticals for Radionuclide Therapy

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2250

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##article.numberofviews## 93

Tatiana Yu Kochetova, Valeriy V Krylov, Valeriy F Stepanenko, Iskander E Musabaev, Sergei A Ivanov, ANDREI D KAPRIN

OF-2520

Safety Assessment of Dose-Escalated 225Ac-PSMA-617 Radioligand Therapy in Patients with Advanced Metastatic Castration-Resistant Prostate Cancer Following Standard Treatment Failure

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2520

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##article.numberofdownloads## 13

##article.numberofviews## 65

MEDICAL PHYSICS

Abuzar Shakeri, Seyede Nasrin Hosseinimotlagh

OF-2470

Carbon radiotherapy of breast tumor with adding high-Z metal nanoparticles using GEANT4 simulation code

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2470

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##article.numberofdownloads## 10

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СИСТЕМАТИЧЕСКИЙ ОБЗОР/МЕТААНАЛИЗ

Sofiia Yuryevna Almeteva, Olga Anatolyevna Titova, Evgeniy Vitalyevich Khmelevsky, Andrey Dmitrievich Kaprin

OF-2281

De-escalation of Radiotherapy in Breast Cancer Patients with Nodal pCR: A Systematic Literature Review

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2281

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##article.numberofdownloads## 14

##article.numberofviews## 80

Pavel I. Bliganov, Marina Vasil'evna Chernykh, Valerii Anatol'evich Ivanov

OF-2468

Incidence of Radionecrosis Following Stereotactic Radiosurgery or Stereotactic Radiotherapy for Brain Metastases: A Meta-Analysis

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2468

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##article.numberofdownloads## 2

##article.numberofviews## 61

EXPERIENCE OF ONCOLOGY CLINICS

Olga V Gribova, Zhanna A Startseva, Viktoria V Velikaya, Evgeniya S Sukhikh, Valery A Novikov, Evgeny L Choynzonov, Ekaterina A Selikhova, Anastasiya I Ryabova

OF-2372

Fast Neutrons Therapy Experience in Tomsk

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2372

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##article.numberofdownloads## 15

##article.numberofviews## 72

Alexei Mikhailovich Karachun , Denis Vladimirovich Samsonov , Moiseenko Andrey Borisovich Moiseenko

OF-2517

Preliminary Efficacy and Safety of a Non-Surgical Watch-and-Wait Strategy in Rectal Cancer: A Prospective Single-Center Observational Study

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2517

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##article.numberofdownloads## 22

##article.numberofviews## 80

Polina A. Lushnikova , Zhanna A. Startseva, Alexey A. Polyakov, Anastasiia E. Arysheva , Evgeniia S. Sukhikh , Irina B. Pyzhova, Viktoria V. Velikaya, Olga V. Gribova

OF-2373

Analysis of Target Coverage Variability and Compliance with Tolerant Doses Using a Fixed Dosimetric Plan for Intracavitary Radiation Therapy for Cervical Cancer. Tomsk City Oncology Center Experience

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2373

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##article.numberofdownloads## 20

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CLINICAL CASES

Kristina Arturovna Komissarova, Timur Raisovich Izmailov

OF-2364

Clinical Case of an Abscopal Effect in a Patient with Hodgkin's Lymphoma Treated with Checkpoint Inhibition and Radiotherapy

https://doi.org/10.37469/0507-3758-2025-71-5-OF-2364

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##article.numberofdownloads## 10

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ANNIVERSARY

Elena A. Dzhenkova

1215-1216

Elena Mikhailovna Franzyants (for the 70 th anniversary of her birth)

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##article.numberofdownloads## 12

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The scientific and practical journal "VOPROSY ONKOLOGII" included in the list of leading peer-reviewed scientific publications of the Higher Attestation Commission of Russia (НАС), recommended for the publication of articles containing materials of candidate and doctoral dissertations. The publication is indexed by the Scopus, Russian Science Citation Index (RSCI) based on Web of Science.

The journal provides immediate open access to its content under the Diamond Open Access model, based on the following principle: free dissemination of academic knowledge among readers - publications are fully accessible to readers free of charge, and there are no publication fees. Full-text materials are available open access under the Creative Commons CC-BY.

The journal is registered with the Federal Service for Supervision of Communications, Information Technology and Mass Media (Roskomnadzor).

Certificate of registration of mass media - PI No. FS77 47156 of 3 November 2011.

ISSN 0507-3758 (Print)
ISSN 2949-4915 (Online)